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filingDate 2015-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-107206049-B
titleOfInvention Methods of treating patients with type 1 hepatorenal syndrome
abstract The principles and embodiments of the present disclosure relate to methods of using terlipressin to treat patients with impaired renal function associated with liver disease. A patient identified as having HRS-1 is tested to determine whether the patient meets at least two of three criteria, wherein the three criteria include WBC <4 or >12 cells/μL; HR >90 bpm; HCO3 < Either 21mmol/L or PaCO2<32mmHg or >20 breaths/min. If the patient meets at least two of the criteria, he or she is administered terlipressin in an amount effective to produce at least a 1.0 mg/dL reduction in serum creatinine.
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