http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107190009-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-30 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-713 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-713 |
| filingDate | 2017-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107190009-B |
| titleOfInvention | siRNA for inhibiting migration of human colorectal cancer cells by silencing ARPC4 gene and application thereof |
| abstract | The invention discloses siRNA for inhibiting migration of human colorectal cancer cells by silencing ARPC4 gene and application thereof. The siRNA is siRNA496 or siRNA538 or siRNA 679. According to the method, the ARPC4 gene is silenced by siRNA, and the change of the migration capacity of the ARPC4 gene to colorectal cancer cells is detected by a western blotting method, a CCK-8 method, flow cytometry and Transwell, so that the expression of the ARPC4 gene in human colorectal cancer SW620 cells can be effectively down-regulated by the siRNA, the migration invasion of the cells is weakened, and therefore, the expression of the ARPC4 gene is specifically interfered by the siRNA, and the ARPC4 gene becomes a new target point for gene therapy of colorectal cancer. |
| priorityDate | 2017-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 122.