| abstract |
The present invention provides a Mycobacterium tuberculosis OS-tb oligosaccharide conjugate and its preparation method and application. In said Mycobacterium tuberculosis OS-tb oligosaccharide conjugate, the chemical structure of the oligosaccharide is clear and single, instead of The mixture can be synthesized in large quantities by chemical methods, and the antigen can be prepared by coupling the linker with the carrier, which can solve the problem of low and unstable immune protection of BCG vaccine, and can also produce better immunity for some special groups with low immunity effect, and has wide application value in the preparation of tuberculosis vaccines. |