http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107164331-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-115 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-40 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0665 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-28 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-16 |
| filingDate | 2017-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107164331-B |
| titleOfInvention | Liver injury targeted mesenchymal stem cell based on miR-221 and preparation method and application thereof |
| abstract | The invention discloses a liver injury targeting mesenchymal stem cell based on miR-221 and a preparation method and application thereof, wherein the liver injury targeting mesenchymal stem cell is prepared by transfecting or infecting nucleic acid by the mesenchymal stem cell, the high expression miR-221 of the liver injury targeting mesenchymal stem cell is specifically prepared by transfecting a miR-221 analogue (mimic or agomir) by a human mesenchymal stem cell or preparing a virus for infecting and expressing miR-221; in order to further improve the efficiency of targeting MSCs to the site of liver injury, and improve the effects of liver function and tissue architecture recovery, mesenchymal stem cells can be treated with basic fibroblast growth factor. The liver injury targeting mesenchymal stem cell has efficient targeting on liver injury, is beneficial to relieving liver fibrosis and improving liver function, has high stability, is convenient to store and transport, is safe to use, and can bring gospel to patients with liver diseases. |
| priorityDate | 2016-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 95.