http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107158378-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0056 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-1869 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0093 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0002 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5169 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0021 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0052 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-143 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-42 |
filingDate | 2017-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-107158378-B |
titleOfInvention | Copper-manganese sulfide protein composite nanoparticle for photothermal effect and preparation method thereof |
abstract | The invention belongs to the field of preparation of photothermal treatment nano composite materials, and particularly relates to a copper sulfide manganese protein composite nano material for photothermal effect and a preparation method thereof. Taking dark green citrate-coated copper sulfide nanocrystal solution as raw material, and adding divalent manganese ions (Mn) 2+ ) And assembling dipyridyl methyl amine (PDA) substituted by boron fluorine pyrrole with the surface of the nano copper sulfide nano crystal, and then applying a method of coating Bovine Serum Albumin (BSA) modified by PEG-FA-COOH to successfully synthesize the novel copper manganese sulfide protein composite nano particle with higher photo-thermal conversion efficiency. The inorganic nano photothermal reagent prepared by the method can be used for multifunctional tumor diagnosis and treatment, can solve the problem of low photothermal effect in tumor photothermal treatment, and is a photothermal diagnosis and treatment agent guided by multifunctional magnetic resonance imaging and light-excited cell fluorescence imaging with low toxicity, biocompatibility and tumor targeting. |
priorityDate | 2017-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 70.