http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107158094-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2236-333 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2236-331 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2236-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2236-39 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-69 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-69 |
| filingDate | 2017-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107158094-B |
| titleOfInvention | Polygala tenuifolia effective part for inhibiting PTP1B activity and preparation and application thereof |
| abstract | The invention provides a polygala tenuifolia effective part for inhibiting PTP1B activity and preparation and application thereof. The preparation method comprises the following steps: weighing a certain amount of polygala tenuifolia medicinal material, adding 95% ethanol, soaking overnight, heating, refluxing, extracting, filtering, and concentrating under reduced pressure until no alcohol smell exists to obtain an alcohol extract; soaking the filtered residue in water overnight, heating under reflux, filtering, and concentrating under reduced pressure to obtain water extract; mixing the ethanol extract and water extract in equal volume, adding petroleum ether, extracting, adding chloroform into the residual liquid after extraction, recovering solvent after extraction, concentrating to obtain extract, drying, and pulverizing to obtain fraction B; the site B has obvious inhibition effect on PTP1B, and can be applied to the preparation of antidiabetic drugs. |
| priorityDate | 2017-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 125.