Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-6068 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-6031 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-57 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-116 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-385 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-095 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-095 |
filingDate |
2017-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2018-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2018-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-107151270-B |
titleOfInvention |
Recombinant ΔfHbp-NadA fusion protein carrier and its preparation method and application |
abstract |
The present invention provides a recombinant ΔfHbp-NadA fusion protein carrier and a preparation method thereof, and further provides a multivalent meningococcal and pneumococcal conjugate vaccine based on the ΔfHbp-NadA protein carrier. Through the design of soft linking peptide chains, the two active proteins are fused and expressed, and then the two become a single protein while maintaining their respective activities. Therefore, it is more controllable in industrial production and immunization, and the risk is greatly reduced. Provides more glycan‑protein binding sites. |
priorityDate |
2017-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |