http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107141307-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-57 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-57 |
filingDate | 2017-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-107141307-B |
titleOfInvention | A kind of preparation method of high-purity cefotetan disodium for injection |
abstract | The invention discloses a kind of preparation methods of high-purity cefotetan disodium for injection; belong to the production purifying process field of cephalosporins; using 7-MAC, acylating agent and isothiazole mono-sodium salt as primary raw material; after acylation reaction, hydrolysis, condensation reaction; clarification is carried out with activated alumina chromatographic column; using decoloration, at salt and purification and etc. after, finally be made Cefotetan Disodium;The present invention can overcome organic solvent residual and be crushed bring quality risk without resin, have better product quality and lower impurity content, and cost is relatively low, easy to operate, energy conservation and environmental protection, is suitble to industrialization production. |
priorityDate | 2017-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 77.