| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_366759959a879950036c4e69dc8fd483 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-232
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-412
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-418
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2420-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2420-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-236
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2420-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-604 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-022
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-084
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-148
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-128
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-10 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-08 |
| filingDate |
2017-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_874f213bc1dac0a89a0f7aaed7bf5ed8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e6ae444e6b8611954ca96ff603eb7aed
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf7190dc9f2da1fa6599fe3ca0293986
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d03875388b15694e965be52ee3485f67
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ec84e29ee08f15fd277f0141fba6e047 |
| publicationDate |
2017-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-107137788-A |
| titleOfInvention |
A method for preparing chitosan/heparinized graphene oxide composite multilayer film on the surface of medical magnesium alloy |
| abstract |
The invention discloses a method for preparing a chitosan/heparinized graphene oxide composite multilayer film on the surface of a medical magnesium alloy. Firstly, negatively charged heparinized graphene oxide is prepared, and then the surface of the medical magnesium alloy is chemically treated. Self-assembled 16-phosphonohexadecanoic acid molecules, and further covalently immobilized chitosan on the surface of magnesium alloy to construct a positively charged material surface, and finally alternately immersed the surface-modified magnesium alloy material into heparinized graphene oxide fully adsorbed in chitosan solution, and obtained chitosan/heparinized graphene oxide composite multilayer film after drying. Using the method of the invention to modify the surface of the medical magnesium alloy can significantly improve the corrosion resistance and biocompatibility of the magnesium alloy, and lay a foundation for the application of the magnesium alloy in the field of implantable medical devices such as vascular stents. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108434515-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111850552-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108707772-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114306740-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108379670-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110833631-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110833631-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108619577-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108379670-B |
| priorityDate |
2017-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |