http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107119095-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y204-99018 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y204-01255 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y204-01257 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y204-01132 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y204-01142 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y306-03001 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1051 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-1278 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-12 |
filingDate | 2009-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-107119095-B |
titleOfInvention | Glycosylated protein expression in prokaryotes |
abstract | The present invention relates to a prokaryotic host cell comprising eukaryotic glycosyltransferase activity, wherein the eukaryotic glycosyltransferase activity is eukaryotic dolichyl-linked UDP-GIcNAc transferase activity and eukaryotic mannosyl transferase activity. Also disclosed are methods of producing glycosylated proteins by providing a prokaryotic host cell comprising eukaryotic glycosyltransferase activity and culturing the prokaryotic host cell under conditions effective to produce the glycosylated protein. Another aspect of the invention relates to a method for screening bacteria or phages by expressing one or more glycans on the surface of bacteria, attaching a label to the surface of said bacteria or on the surface of phage derived from said bacteria on one or more glycans and analyze the markers in a high-throughput format. Also disclosed are glycosylated antibodies comprising an Fv portion that recognizes and binds native antigen and an Fc portion that is glycosylated at conserved asparagine residues. |
priorityDate | 2008-01-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 830.