| abstract |
The invention belongs to field of medicine and chemical technology, it is related to the preparation method and purposes of salt compounds in thiazole.In particular it relates to the preparation method and medical usage of compound of formula I.Specifically, the preparation method includes the following steps: that, by compound A and 1,2- propylene oxide reacts to obtain compound B, Wherein the X in Compound A structure formula is chlorine, bromine or iodine； Wherein: n 0.Compound of formula I is a kind of potent crosslinking protein decomposition agent, and stable structure, and physicochemical property is excellent, has good pharmacological action；The available quality of large-scale production is stable, controllable reliable sample, is suitable as drug development. |