Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8f8fe90bd741939b669967410a817918 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y204-01092 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-41 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1051 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y204-01038 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y204-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-10 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00 |
filingDate |
2015-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ed9ac967d4802e4ade2ed9ae467c70e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c91ed2febc80730af6d1ec826afb56a2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5cf036e3fec8e73880f0f905956be0c5 |
publicationDate |
2017-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-107109454-A |
titleOfInvention |
Method for modifying glycoprotein with β‑(1,4)‑N‑acetylgalactosamine transferase or mutant thereof |
abstract |
The invention relates to a method for modifying glycoprotein with β-(1,4)-N-acetylgalactosamine transferase or a mutant thereof. The method comprises the step of derivatizing a glycoprotein comprising a glycan comprising a terminal GlcNAc moiety with a non-native sugar in the presence of β-(1,4)-N-acetylgalactosamine transferase or a mutant thereof Nucleotide contacts. The non-natural sugar derivative nucleotide is shown in formula (3): wherein A is selected from -N3 ; -C(O) R3 ; -C≡C - R4; -SH; -SC(O) R8 ; -SC(V) OR8 , wherein V is O or S; -X, wherein X is selected from F, Cl, Br and I; -OS(O) 2 R 5 ; optionally substituted C 2 -C 24 alkyl; optionally substituted terminal C 2 -C 24 alkenyl; Optionally substituted terminal C 3 -C 24 propadienyl. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110195043-A |
priorityDate |
2014-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |