http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107106701-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6889 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6851 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6855 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6811 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6803 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate | 2015-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-107106701-B |
titleOfInvention | Sulfonamide linkers, conjugates thereof, and methods of making |
abstract | The present invention relates to compounds comprising an alpha-terminal and an omega-terminal, said compounds comprising a reactive group Q at the alpha-terminal 1 And comprises a target molecule at the omega-terminus, said Q 1 Capable of interacting with functional groups F present on biomolecules 1 A reaction, said compound further comprising a group of formula (1) or a salt thereof; the compounds may also be referred to as linker-conjugates. The invention also relates to a method for preparing a bioconjugate, said method comprising reacting a reactive group Q of a linker-conjugate of the invention 1 Functional groups F with biomolecules 1 And (3) a step of reaction. The invention also relates to bioconjugates obtainable by the method of the invention. In a preferred embodiment, the invention relates to a process for preparing bioconjugates by cycloaddition, such as (4+2) -cycloaddition (e.g. diels-alder reaction) or (3+2) -cycloaddition (e.g. 1, 3-dipolar cycloaddition). |
priorityDate | 2014-10-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 304.