http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107102083-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02 |
| filingDate | 2017-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107102083-B |
| titleOfInvention | PHBA process impurity detection method |
| abstract | The invention discloses a PHBA process impurity detection method, which adopts normal phase high performance liquid chromatography, wherein the chromatographic conditions are as follows: a chromatography column C18 column or a C8 column; mobile phase composition aqueous phase: acetonitrile =70:30-40: 60; flow rate of mobile phase: 0.7-1.0 mL/min; detection wavelength: 220-280 nm; column temperature: 20-40 ℃; a detector: an ultraviolet detector or a diode array detector; the method realizes the separation of the PHBA from the process impurity A and the process impurity B, has high sensitivity and specificity, is simple and convenient to operate, has the separation degree of more than 1.50, accords with the specification of pharmacopoeia, can be used for the quality control of the PHBA, has the peak time within 10min, is quick and efficient in detection method, and has good industrial practicability. |
| priorityDate | 2017-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.