http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107075481-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-155 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-115 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2506-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2506-45 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0616 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0618 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0031 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0037 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0606 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0735 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0797 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-079 |
| filingDate | 2015-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107075481-B |
| titleOfInvention | Method for preparing adenohypophysis or precursor tissue thereof |
| abstract | The present invention provides methods for deriving adenohypophysis or precursor tissue thereof from human pluripotent stem cells in vitro. In this method: a hypothalamic neuroepithelial tissue and epidermal ectoderm are obtained by culturing human pluripotent stem cell aggregates in suspension in a medium containing bone morphogenetic factor signaling pathway activators and Shh signaling pathway active substances of human cell aggregates; and by subjecting the resulting human cell aggregates comprising hypothalamic neuroepithelial tissue and epidermal ectoderm in a medium containing bone morphogenetic factor signaling pathway activators and Shh signaling pathway active substances Further suspension culture induces the formation of pituitary placodes and/or latke sacs in the epidermal ectoderm, resulting in human cell aggregates comprising 1) hypothalamic neuroepithelial tissue and 2) pituitary placodes and/or latke sacs. |
| priorityDate | 2014-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 540.