http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107074921-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2469-20 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6854 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56905 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-564 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
| filingDate | 2015-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107074921-B |
| titleOfInvention | Recombinant Trypanosoma cruzi JL7 antigenic variants and their use in the detection of Chagas disease |
| abstract | The present invention relates to variants of the JL7 antigen suitable for the detection of antibodies against Trypanosoma cruzi (causing Chagas disease) in isolated biological samples. These antigens comprise a JL7-specific amino acid sequence consisting of two copies of SEQ ID NO. 2, wherein each of the two copies is at least 90% amino acid identical to SEQ ID NO. 2 and wherein no further Trypanosoma cruzi-specific amino acid sequences are present in the polypeptide. The present invention also relates to a composition of polypeptides useful for the detection of antibodies against Trypanosoma cruzi comprising the JL7 antigen characterized above together with at least one of the Trypanosoma cruzi polypeptides 1F8, Cruzipain, KMP-11 and PAR-2. Furthermore, it relates to a method for producing the JL7 antigen and a diagnostic method for detecting Trypanosoma cruzi antibodies using the JL7 polypeptide. Furthermore, the present invention relates to a kit comprising a composition of the JL7 polypeptide or the Trypanosoma cruzi polypeptide. |
| priorityDate | 2014-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 117.