http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107056853-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-203 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C273-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C273-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7034 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-203 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 |
| filingDate | 2017-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107056853-B |
| titleOfInvention | Gastrodin compound and preparation method, preparation and application thereof |
| abstract | The invention discloses a gastrodin compound, and a preparation method, a preparation and application thereof. The gastrodin compound is a eutectic crystal of a compound shown in a formula (I) and urea, and the structural formula of the compound shown in the formula (I) is as follows: the preparation method comprises the step of reacting gastrodin and urea in an organic solvent system to obtain the gastrodin-urea composite material, wherein the organic solvent is one or more of alcohols, ketones, alkyl nitriles and cyclic ethers. The preparation is prepared by adding pharmaceutically acceptable adjuvants into the gastrodin compound to obtain powder, granule, tablet, capsule and pill. The application is the application of the gastrodin compound in preparing the medicine for preventing/treating cardiovascular and cerebrovascular diseases. The cocrystal of gastrodin and urea provided by the invention has high solubility, is beneficial to improving the absorption efficiency of the medicament and improving the bioavailability of the medicament, and has important significance for improving the curative effect and safety of the medicament. |
| priorityDate | 2017-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.