http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107056721-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D261-08 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D261-08 |
filingDate | 2017-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-107056721-B |
titleOfInvention | A kind of Parecoxib Sodium crystalline compounds and preparation method thereof |
abstract | The invention belongs to pharmaceutical technology field, a kind of Parecoxib Sodium crystalline compounds and preparation method thereof are disclosed.Parecoxib Sodium crystalline compounds of the invention are different from the prior art, it is SC 69124 sodium-hydrate, its X-ray powder diffraction collection indicated with the 2 θ ± 0.2 ° angles of diffraction shows characteristic diffraction peak at 2.055 °, 3.045 °, 3.727 °, 9.849 °, 11.636 °, 14.209 °, 27.418 °, 28.636 °, 30.582 °, 31.418 °, 32.436 °, 34.018 °, 35.782 °, 36.927 °, 38.618 °, and the X-ray powder diffraction spectrogram obtained using Cu-K alpha ray measurement is as shown in Figure 1.Parecoxib Sodium crystalline compounds stability disclosed by the invention is not good, easy to moisture absorption under high humidity state, and preparation method is simple to operation, and drug safety greatly improves, and is very suitable to clinical application. |
priorityDate | 2017-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 37.