| abstract |
The invention belongs to the field of medicines, and particularly relates to a 4-aminopyrimidine compound with structural characteristics of a formula (I) or a pharmaceutically acceptable salt thereof, a preparation method thereof, and application thereof as a Bruton's Tyrosine Kinase (BTK) inhibitor. The experimental result shows that the compound has a remarkable inhibiting effect on BTK, and can be used for treating diseases such as thromboembolism, inflammatory diseases, autoimmune diseases, Waldenstrom macroglobulinemia, B cell lymphoma and the like. |