http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107041952-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5258 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-32334 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-125 |
| filingDate | 2016-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107041952-B |
| titleOfInvention | Vaccine with surface modified with alumina, preparation method thereof and vaccine composition |
| abstract | The invention relates to the technical field of biology, and discloses a vaccine with boehmite crystal form alumina modified on the surface, a preparation method thereof and a vaccine composition, wherein each milligram of the vaccine to be modified or each 1X 10 8 The modification amount of the boehmite crystal form alumina on the PFU live vaccine to be modified is 5-500 mu g calculated by aluminum element. The method for preparing the vaccine comprises the following steps: and mixing the boehmite crystal form alumina sol and the vaccine to be modified for incubation. The invention also discloses a vaccine composition containing the vaccine and an adjuvant. The vaccine with the aluminum oxide on the surface shows good thermal stability and obviously improved immunogenicity. The vaccine can be prepared, stored and reserved under the condition of solution, complex treatment processes such as freeze-drying, recombination and the like are omitted, the dependence of the vaccine on a cold chain is reduced to a great extent, and the vaccine has good economic benefit and social benefit. |
| priorityDate | 2016-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 52.