| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42e94091a4fc81b8d0237117707cc7ee |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-546
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-545
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-593
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-46 |
| filingDate |
1992-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b31beeaeabe12153da5f43081409b5f6 |
| publicationDate |
1993-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-1070406-A |
| titleOfInvention |
Preparation of cephalosporin antibiotics from cis-isomers of thiazolyl intermediates |
| abstract |
The present invention provides an aqueous acylation process for the preparation of the antibiotic Cefepime dihydrochloride hydrate substantially free of the trans isomer and the Δ2 isomer, the process comprising the use of 2-(2-aminothiazole -4-yl)-cis isomer of 2-methoxyiminoacetyl chloride hydrochloride p-7-amino-3-[(1-methyl-1-pyrrolidinyl)-methyl]cephalosporin- 3-ene-4-carboxylates undergo N-acylation. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108285436-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-1824658-B |
| priorityDate |
1991-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |