http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107034177-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-30 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0609 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-075 |
| filingDate | 2017-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107034177-B |
| titleOfInvention | Bovine vacuolar membrane cell in-vitro culture regulator and application thereof |
| abstract | The invention provides a regulator for in-vitro culture of bovine theca cells, which takes in-vitro culture solution of the bovine theca cells as a matrix, and the matrix contains melatonin. When the bovine theca cells are cultured by using the in-vitro culture solution added with the melatonin, the melatonin can inhibit the synthesis of progesterone of the bovine theca cells and inhibit StAR and CASP3 expression induced by LH + IGF1, but has no influence on CYP11A1 and CYP17A1 expression. However, melatonin can promote the proliferation of bovine theca cells, and as an endocrine regulatory factor of bovine ovarian function, melatonin can inhibit the effects of LH and IGF1 by down-regulating the synthesis of steroid hormones, thereby delaying the differentiation of the membrane cells. The melatonin is applied to a preparation for promoting the membrane cell proliferation or inhibiting the synthesis of steroids of bovine theca cells, and has good application value. |
| priorityDate | 2017-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 128.