http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107033148-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 |
| filingDate | 2017-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107033148-B |
| titleOfInvention | Triazole containing pyrimido-mercapto tetrazole class LSD1 inhibitor, preparation method and application |
| abstract | The invention belongs to medicinal chemistry art, the compound of a kind of triazole containing pyrimido-mercapto tetrazole class formation, preparation method are disclosed and its with lysine specificity demethylase（Hereinafter referred to as LSD1）As target application in preparation of anti-tumor drugs.The compounds of this invention general formula is as shown in I. External LSD1 enzyme inhibition activities are it is demonstrated experimentally that such compound is applied to antitumor drug and prepares by inhibiting the activity of LSD1 to can be used as the lead compound further developed to kinds of tumor cells with apparent inhibition and lethal effect. |
| priorityDate | 2017-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 121.