http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107033100-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-64 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-64 |
| filingDate | 2017-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107033100-B |
| titleOfInvention | A kind of benzothiazole derivant, preparation method and its medical usage |
| abstract | The present invention relates to field of medicinal chemistry, more particularly to a kind of benzothiazole derivant (Formulas I) with anti-inflammatory activity, Preliminary activation test proves that the compounds of this invention has good Keap1-Nrf2 protein protein interaction inhibitory activity, it may interfere with the combination of Keap1-Nrf2, to activate Nrf2, with potential anti-inflammatory activity, it can be used for treating numerous diseases relevant to inflammation, such as tumour, Parkinson's disease, senile dementia, Chronic Obstructive Pulmonary Disease, the hardening of artery congee, chronic kidney disease disease, diabetes or rheumatoid arthritis. |
| priorityDate | 2017-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 101.