http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107033091-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-95 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-95 |
filingDate | 2017-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-107033091-B |
titleOfInvention | Piperazine derivative and preparation method and application thereof |
abstract | The invention discloses a piperazine derivativeA preparation method and application of the piperazine derivative belong to the technical field of organic synthesis, and the piperazine derivative has the following general formula: wherein R is pyridyl or diphenyl or substituted phenyl containing chloro, fluoro, methoxy, hydrogen, methyl or nitro. The invention introduces quinazolinone with good anticancer activity into phenylpiperazine ring to prepare the phenylpiperazine derivative containing quinazolinone, has obvious inhibition effect on the growth of breast cancer cells, and can be applied to the preparation of anti-breast cancer drugs. |
priorityDate | 2017-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 98.