http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107033064-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-40 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-06 |
| filingDate | 2017-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107033064-B |
| titleOfInvention | A kind of 3- (morpholine replaces fragrant imido grpup) Benzazole compounds and its preparation method and application |
| abstract | The present invention provides a kind of 3- (morpholine replaces fragrant imido grpup) Benzazole compounds, such compound structure is simple, simple synthetic method, in active testing, part of compounds shows certain anti-Kv1.5 bioactivity and selectivity, wherein compound T16 is shown higher inhibiting rate (IR=70.8%) in 100 μM of levels, and compound T5 also shows certain inhibitory activity (IR=57.5%) in 100 μM of levels.Compound also shows certain target selectivity to the channel Kv1.5 simultaneously.The present invention also provides the applications in the preparation method of 3- (morpholine replaces fragrant imido grpup) Benzazole compounds and its drug design and development of preparation treatment auricular fibrillation. |
| priorityDate | 2017-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 117.