http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107033045-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-54 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C319-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P11-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C319-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P11-00 |
| filingDate | 2017-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107033045-B |
| titleOfInvention | A kind of preparation method of high-purity natural garlic 4,5,9-trithiadodeca-1,6,11-triene 9-oxide |
| abstract | The invention discloses a kind of preparation method of high-purity natural garlic 4,5,9-trithiadodeca-1,6,11-triene 9-oxide, include the following steps: that (1) crushes garlic, after the first solvent is added, spontaneous fermentation obtains product A；(2) product A is mixed with the second solvent, ultrasonic extraction, obtains product B；(3) product B passes through supercritical CO 2 Device extraction and separation obtain product C；(4) product C is isolated and purified by process-scale chromatography, and being collected into the eluent rich in 4,5,9-trithiadodeca-1,6,11-triene 9-oxide is product D；(5) product D, which is concentrated under reduced pressure, removes solvent, obtains the Natural Garlic 4,5,9-trithiadodeca-1,6,11-triene 9-oxide product that purity is greater than 98%.Method provided by the invention is fermented using the allinase that garlic itself contains, and by ultrasonic wave extraction 4,5,9-trithiadodeca-1,6,11-triene 9-oxide, recycles supercritical CO 2 Abstraction technique purifies 4,5,9-trithiadodeca-1,6,11-triene 9-oxide, finally using the 4,5,9-trithiadodeca-1,6,11-triene 9-oxide product of industry chromatography technique preparation high-purity.The simple process, stabilization, 4,5,9-trithiadodeca-1,6,11-triene 9-oxide purity is high, to prepare 4,5,9-trithiadodeca-1,6,11-triene 9-oxide standard substance, research and development new drug provides basis. |
| priorityDate | 2017-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.