abstract |
The present disclosure provides an antibody drug complex (ADC) having chemical formula (I) or a pharmaceutically acceptable salt or solvate thereof. In the chemical formula (I), p is an integer ranging from 1 to 26, A is an antibody, and -(L-D) is a linker-drug unit. Wherein, L is a linker unit with glycopeptide, and D is a drug unit. Wherein, the antibody is linked to the composite unit through a cysteine residue of the antibody. The present disclosure also provides a method for producing an antibody-drug complex (ADC). A-(L-D) p (I). |