| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e4ff9e16ae7a71e7c0920da0a77f0785 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-713
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7105
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7105
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-06 |
| filingDate |
2017-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ff5ae58c7c9f71684e2dc9d3e1a73e8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_55823e84447d8a5573c9e7d88ce57282
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f8863115a28b3a4a7ecab3752c0bca70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_40f056a16b23be29dbfa4ea6ced0e610 |
| publicationDate |
2017-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-107028972-A |
| titleOfInvention |
LncRNAsENST00000607393 SiRNA prepare the application for the treatment of glaucoma agents |
| abstract |
It is an object of the invention to provide a kind of applications of lncRNAs ENST00000607393 SiRNA on treatment glaucoma agents are prepared.The present invention specify that ENST00000607393 expressions and the correlation of the primary tm cells calcification of people, and we disturb the expression of ENST00000607393 in the lower primary tm cells of mediator to the 46.21% of control group by siRNA first.Under conditions of 500 μm of ol/L hydrogenperoxide steam generators intervene cell 48 hours, it is observed that for control group, ENST00000607393 expression, which is lowered, can significantly reduce the primary tm cells ALP activity of people, and then the primary tm cells calcification level of people can be significantly reduced, play a part for the treatment of or preventing glaucoma. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11160824-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018223846-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018223849-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018223847-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108753969-A |
| priorityDate |
2017-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |