http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107022591-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-62 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-84 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 |
filingDate | 2017-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2018-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2018-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-107022591-B |
titleOfInvention | A kind of Pichia pastoris fermentation process for improving insulin and the like precursor expression |
abstract | The present invention relates to field of biological pharmacy, and in particular to a kind of Pichia pastoris fermentation process for improving insulin and the like precursor expression.Fermented and cultured is divided into initial growth phase, glycerine adds stage and methanol induction phase.This method is by controlling initial culture medium formula, nitrogen source types and carbon source additional way and being extended in the fermentation middle and later periods by continuously or semi-continuously adding the organic nitrogen source fermentation period of a small amount of microorganism or plant origin.Ensure target product quality while, more than 30% output increased. |
priorityDate | 2017-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 133.