http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107021969-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-584 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D513-04 |
filingDate | 2017-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2018-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2018-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-107021969-B |
titleOfInvention | The method that catalysis oxidation prepares biotin precursor ketone acid |
abstract | The invention discloses a kind of methods that catalysis oxidation prepares biotin precursor ketone acid, with (3S, 7R, 7aR) -6- benzyl -7- (2- oxygen cyclohexyl) -3- phenyl tetrahydro -5H- imidazoles [1,5-c] [1,3] thiazole -5- ketone be raw material, using molecular oxygen as oxidant, under the action of catalyst, it is prepared through direct oxidation;The catalyst includes major catalyst and co-catalyst, and major catalyst is metal iron compound, and co-catalyst is selected from organic solvent.The present invention provides a variation routes, improve the yield and selectivity of product, realize the recovery of catalyst, reduce production cost and three waste discharge, while overcoming the catalysis oxidation problem for the big steric hindrance alpha-substituted ketone that conventional method cann't be solved. |
priorityDate | 2017-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 83.