http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107014998-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2440-10 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57484 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57423 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate | 2017-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-107014998-B |
titleOfInvention | A kind of lung cancer regulatory factor SRSF5 and its inhibitor and application |
abstract | The invention discloses a kind of lung cancer regulatory factor SRSF5 and its inhibitor and applications.The present invention plays a driving role for lung cancer by the regulation unbalance shaft that the tumor formation in nude mice of the proliferation experiment of cytology level, plate clone formation experiment and Ex vivo animal integral level demonstrates SRSF5-CCAR1.Above-mentioned description of test SRSF5-CCAR1 signal shaft can be used as potential lung cancer therapy target, enrich the understanding to the activity regulation mechanism of splicing factor.The screening of micromolecular inhibitor or montage Active Regulation inhibitor based on SRSF5-CCAR1 signal shaft will provide new thinking and important scientific basic for the targeted therapy of lung cancer. |
priorityDate | 2017-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 34.