http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107011288-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-073 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-073 |
| filingDate | 2017-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107011288-B |
| titleOfInvention | A kind of preparation method of aripiprazole intermediate 1- (2,3- dichlorophenyl) piperazine hydrochloride |
| abstract | The invention discloses a kind of preparation methods of aripiprazole intermediate 1- (2,3- dichlorophenyl) piperazine hydrochloride.This method is that starting material is reacted using one kettle way with 2,3 dichloronitrobenzenes, bis- (2- chloroethyl) amine hydrochlorates.This method is easy to operate, and the acid chlorization hydrogen generated in reaction process is dissolved in the reduction that nitro is participated in ammonium chloride solution, not only save the cost but also can be with energy conservation and environmental protection, and easy to operate, high income, cost are lower is suitable for industrialized production. |
| priorityDate | 2017-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 47.