http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107011220-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b9c0f7fbe564805befc9b55b4819d25a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C315-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C317-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D263-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C317-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C315-04 |
| filingDate | 2017-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a15c7022587bfb95807c9deca7170c9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe75e68770a051f4894dc45d29eeac4f |
| publicationDate | 2017-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107011220-A |
| titleOfInvention | Thiamphenicol tetrafluoro propionic ester and its preparation method and application |
| abstract | The present invention relates to a kind of Thiamphenicol tetrafluoro propionic ester and its preparation method and application, specify that Thiamphenicol tetrafluoro propionic ester is unknown impuritie contained by Florfenicol, and its preparation method is：By (4R, 5R) 2 dichloromethyl 4, (4 methylsulfonyl phenyl) the 4 oxazole methanol of 5 dihydro 5 and N, N diethyl 1,1,2,3,3,3 hexafluoro propylamine carry out reacting [(4R, 5R) dihydro 5 of 2 dichloromethyl 4,5 (base of 4 methylsulfonyl phenyl) oxazoles 4] methanol 2,3,3, after 3 tetrafluoro propionic esters, obtained through hydrolysis, the product of synthesis and separating obtained impurity have identical mass spectrum and 1 H H NMR spectroscopies.The Thiamphenicol tetrafluoro propionic ester synthesis technique that the present invention is designed has the advantages that raw material is easy to get, reaction condition is gentle, course of reaction is easily controlled, and provides satisfactory reference substance for Florfenicol quality control, can greatly improve drug safety. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111333553-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111333553-A |
| priorityDate | 2017-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 79.