Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-439 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-04 |
filingDate |
2015-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2020-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2020-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-107001366-B |
titleOfInvention |
Crystallization of Diazabicyclooctane Derivatives and Preparation of Stable Lyophilized Formulations |
abstract |
The object of the present invention is to provide a method by which crystals of compound (I) can be easily prepared on an industrial scale, and a stable lyophilized composition of compound (I). It has been found that by lyophilizing an aqueous solution containing compound (I) and an inorganic salt such as sodium chloride, a lyophilized composition in which compound (I) is a crystal with good storage stability can be obtained. Crystals of compound (I) were obtained from the aqueous solution. |
priorityDate |
2014-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |