http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106995697-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1466 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0032 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06 |
filingDate | 2017-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-106995697-B |
titleOfInvention | Fluorescent labeled sugar molecule and preparation method and application thereof |
abstract | The invention relates to a fluorescent labeled sugar molecule and a preparation method and application thereof. The invention adopts a reductive amination method to introduce amino-containing molecules at the reducing end of sugar molecules, then couples the amino-containing sugar molecules with carboxyl-containing fluorescent molecules, and purifies the products after reductive amination and fluorescent labeling respectively by dialysis and gel filtration methods to finally obtain the fluorescent labeled sugar molecules. The fluorescent labeled sugar molecule prepared by the invention is used for the metabolism dynamics of the sugar molecule and the distribution research of tissues and organs in living animals. The sugar molecule fluorescence labeling method provided by the invention has the advantages of simple operation, good repeatability, wide application range, low cost and the like, can be used for labeling any sugar molecule containing a reduction end, and adopts a living body imager to research the metabolism and tissue organ distribution of the sugar molecule in an animal body. |
priorityDate | 2017-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 55.