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classificationCPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-06
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-205
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P33-00
classificationIPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-06
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P33-00
filingDate 2017-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2020-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-106987542-B
titleOfInvention Application of Arthrobacter simplex mutant strain in 1, 2-position dehydrogenation
abstract The invention discloses Arthrobacter simplexArthrobacter simplex) mutant strain capable of producing C in one-step fermentation 23 H 26 O 4 It is preserved in China general microbiological culture Collection center (CGMCC) with the preservation number of CGMCC No. 13665. C 23 H 26 O 4 Is an important intermediate of dexamethasone, betamethasone, methylprednisolone and the like, and C can be converted by adopting the Arthrobacter simplex with the preservation number of CGMCC No.13665 23 H 28 O 4 Dehydrogenation to produce C 23 H 26 O 4 And will not be to C 17 The bit tail chain is hydrolyzed, the feed concentration of the substrate is 2.0%, the weight yield can reach 90-95%, the purity is more than or equal to 90%, the impurity amount is less, the production cost is lower, and the industrial production requirement can be met.
priorityDate 2017-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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