http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106986955-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0003 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0075 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-10 |
filingDate | 2017-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-106986955-B |
titleOfInvention | The Azide method of modifying and Azide heparin of a kind of heparin and application |
abstract | The invention belongs to the technical field of biomaterial, Azide method of modifying and Azide heparin and the application of a kind of heparin are disclosed.It the described method comprises the following steps: (1) being activated the azido compound containing carboxyl using activating reagent, the azido compound activated;The condition of the activation processing are as follows: 0~1~14h is reacted at room temperature;(2) heparin salting liquid is added into the azido compound of the activation of step (1), adjusts pH to 7~9, in 0~reacted at room temperature, dialysis removal small molecule is dry, obtains Azide heparin.Method of the invention is simple, successfully modifies onto heparin molecule chain azido group, has obtained Azide heparin.The Azide heparin can preferable modified biological material, heparin is introduced into biomaterial in the form of chemical bond, has expanded the application field of heparin. |
priorityDate | 2017-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 78.