| abstract |
The present invention provides a medicament having, as an active ingredient, a compound that is useful in the prevention and/or treatment of Trk-related diseases such as cancer, pain, pruritus, lower urinary tract disorders, asthma, allergic rhinitis, inflammatory bowel disease or Trk inhibitory activity in Chagas disease). The compound represented by the general formula (I) (in this formula, all symbols have the same meaning as the symbols in the specification), its salts, its N-oxides, its solvates or its prodrugs are used as pharmaceutical ingredients, It has Trk inhibitory activity in the prevention and/or treatment of pain, pruritus, lower urinary tract disorders, asthma, allergic rhinitis, inflammatory bowel disease or Chagas disease and other such conditions. |