http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106986766-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-935 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-367 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-736 |
filingDate | 2017-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-106986766-B |
titleOfInvention | Preparation method of tafluprost |
abstract | The invention discloses a preparation method of tafluprost, which comprises the steps of taking a compound shown in a formula 1 as a raw material, and carrying out DIBAL-H reduction, Wittig reaction and esterification reaction; wherein, basic amino acid is adopted for refining after the wittig reaction. The total mass yield of the three-step reaction of the preparation method can reach 70 percent, the process is stable, the prepared tafluprost product is colorless to light yellow viscous oily liquid, and the purity is as high as more than 99 percent. |
priorityDate | 2017-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 41.