http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106979942-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_786330ef065dd3c4e0a27d0108098ef9 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-658 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-65 |
filingDate | 2017-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a357dea4f6d721a63073a39ac2dc303a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f742cb7be59988878fc10d5e20e7c89 |
publicationDate | 2017-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-106979942-A |
titleOfInvention | A Raman spectroscopic analysis method for individual quantification of solid-phase synthetic compound combinatorial library and its application |
abstract | The invention discloses an individual quantitative Raman spectroscopic analysis method for a solid-phase synthetic compound library and its application. The method uses a molecule with a strong Raman signal within a wave number of 2000-2500cm -1 as a Raman signal source , the signals of such molecules are not affected by other functional groups, effectively solving the influence of other Raman signals. The connection reaction efficiency of the Raman signal molecule and the target compound is high. In the analysis method, the solid-phase synthesis yield of the target compound obtained is proportional to the relative Raman signal intensity; For the characterization of the carrier, the compound yield distribution map of the combinatorial library can be obtained, and its quantitative data include indicators such as the maximum peak value and uniformity (distribution width) of the yield. The analysis method can be used for quantitative analysis of functional groups of solid-phase synthesis products, yield analysis of individual compounds in solid-phase synthesis combinatorial libraries, and yield distribution analysis and quality monitoring of solid-phase synthetic compound combinatorial libraries. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112683874-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108362679-A |
priorityDate | 2017-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 41.