http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106978418-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-15043 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-141 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1137 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-713 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-713 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-867 |
| filingDate | 2017-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106978418-B |
| titleOfInvention | shRNA interference sequence of human PYCR1 gene and application thereof |
| abstract | The invention discloses an application of a human PYCR1 gene and related medicines thereof. The invention discloses the use of human PYCR1 gene in tumor treatment, tumor diagnosis and medicine preparation. The invention further constructs human PYCR1 gene small interfering RNA, a human PYCR1 gene interfering nucleic acid construct and a human PYCR1 gene interfering lentivirus and discloses the application thereof. The siRNA or the nucleic acid construct containing the siRNA sequence and the lentivirus provided by the invention can specifically inhibit the expression of the human PYCR1 gene, particularly the lentivirus can efficiently infect target cells, efficiently inhibit the expression of the PYCR1 gene in the target cells, further inhibit the growth of tumor cells and promote the apoptosis of the tumor cells, and have important significance in tumor treatment. |
| priorityDate | 2017-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 175.