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filingDate 2017-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8fa60503e6bc6b1b45e187dae9ab948a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1804f9bf3724dcdd764bd778df4208f4
publicationDate 2017-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-106977732-A
titleOfInvention A kind of preparation method of polyacrylic acid PPDO MPEGPLA copolymer micelles
abstract The present invention discloses a kind of preparation method of polyacrylic acid PPDO MPEGPLA copolymer micelles, using following steps:1)Addition polymerization acrylic acid, hydroxy-end capped PPDO monododecyl ether, solvent and condensing agent in reactor, react to obtain polyacrylic acid PPDO graft copolymer;2)Adjunction graft copolymer, hydroxy-end capped MPEGPLA, solvent and condensing agent in reactor, react to obtain polyacrylic acid PPDO MPEGPLA dual graft copolymers;3)Add dual graft copolymer and solvent in reactor, dissolve to obtain dual graft copolymer stoste;4)Stoste is added into bag filter, the beaker for filling selective solvent is put into, is replaced 3~4 times, is poured into graduated volumetric flask, be adjusted to scale, obtain object of the present invention.Preparation technology of the present invention is simple, be easy to grasp, and gained object is a kind of new pharmaceutical carrier.
priorityDate 2017-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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