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filingDate 2017-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2020-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-106977585-B
titleOfInvention Two-photon fluorescence probe library for photodynamic therapy by mitochondria positioning and application thereof
abstract The invention relates to a two-photon fluorescence probe library for mitochondrial positioning in photodynamic therapy and application thereof, belonging to the field of organic fluorescence probes. The invention develops a series of mitochondrion targeted two-photon fluorescent probes with photodynamic therapy, which has the advantages of cheap and easily obtained raw materials, simple and convenient operation, mild reaction conditions, low production cost and convenient industrialization, and has the chemical structure characteristics of mainly comprising a mitochondrion targeted group and an optical regulation and control group in a linkage way. The probe can be applied to detection and diagnosis of human health/diseases, for example, mitochondria can be accurately targeted by the probe, so that early warning of diseases can be achieved.
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