http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106977571-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J9-005 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 |
filingDate | 2017-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-106977571-B |
titleOfInvention | A kind of Austria's shellfish cholic acid analogue and its preparation method and application |
abstract | The invention discloses a kind of shellfish cholic acid analogue difficult to understand, which is 3 α, 7-5 β of alpha-dihydroxy-23- ethyl-cholanic acid (II).The preparation method of shellfish cholic acid analogue difficult to understand is also disclosed, shellfish cholic acid analogue difficult to understand is obtained through esterification or substitution reaction, again through hydroxyl protection reaction, the derivative, the decarboxylation reaction that with alkyl halide react to obtain shellfish cholic acid analogue difficult to understand by chenodeoxycholic acid.The present invention can provide standard reference material for the quality control of shellfish cholic acid difficult to understand and clinical application safety detection, ensure that clinical application is safe and reliable.Preparation method of the invention is easy to operate, and reaction condition is mild, and yield is higher, gained Austria shellfish cholic acid analogue purity is high. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102106943-B1 |
priorityDate | 2017-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 77.