http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106977563-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-203 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-203 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-00 |
filingDate | 2017-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-106977563-B |
titleOfInvention | A kind of synthetic method of deuterium-labeled glucosiduronate retinamide |
abstract | The invention discloses a kind of synthetic methods of deuterium-labeled glucosiduronate retinamide, and this method is with 4- nitrophenol-D 4 For deuterium-labeled starting material, synthesize to obtain deuterium-labeled glucosiduronate retinamide-D through six-step process 4 .The present invention filters out optimal preparation step and reaction condition by many experiments, and entire technological design is reasonable, strong operability, the deuterium-labeled glucosiduronate retinamide that the present invention is prepared, purity is up to 98% or more, and yield is up to 70% or more, and isotope abundance > 99%.Deuterium-labeled metabolin of the deuterium-labeled glucosiduronate retinamide that the present invention is prepared as retinamide, can study for the metabolic mechanism of retinamide and the research of antitumor machanism is provided for examination and control sample, have important application value. |
priorityDate | 2017-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 60.