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filingDate 2017-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2018-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2018-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-106970215-B
titleOfInvention A kind of preparation method of the Fe3O4@PEG@SiO2 artificial antibodies of detection thifensulfuronmethyl
abstract A kind of Fe of detection thifensulfuronmethyl 3 O 4 @PEG@SiO 2 The preparation method of artificial antibody, is included in Fe 3 O 4 The surface modification polyethylene glycol 2000 of magnetic nano-particle, surface coated Si O 2 Shell forms core shell shell structure, is located at SiO by elution 2 Imprint molecule in shell forms the specific recognition site hole having the function of with imprint molecule structure, size and base complementation, realizes to target analyte molecule Selective recognition and detection.Artificial antibody's preparation process includes following three step:First, Fe is made 3 O 4 Magnetic nano-particle and in its surface modification polyethylene glycol;Then, target molecule thifensulfuronmethyl, crosslinking agent and catalyst is added, hydrolyze imprint surface thifensulfuronmethyl Fe 3 O 4 @PEG@SiO 2 Particle;Finally, it is 1 with volume ratio:4 acetic acid and acetone mixture eluted template molecule, obtains the Fe with Selective recognition imprint molecule 3 O 4 @PEG@SiO 2 Artificial antibody is 41.28mg/g to the maximum saturation binding capacity of thifensulfuronmethyl, and in preceding 30min, rate of adsorption 0.45mg/gmin is 5.34 times and 3.46 times of non-imprinting method respectively.
priorityDate 2017-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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