http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106970059-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-188 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6486 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G83-008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6402 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G83-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 |
| filingDate | 2017-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106970059-B |
| titleOfInvention | Preparation and application of two-photon fluorescent probe |
| abstract | The invention belongs to the field of nano biomedical diagnosis and treatment, and mainly relates to preparation of an organic/inorganic composite nano material system with good biocompatibility and application of the organic/inorganic composite nano material system in biological two-photon imaging and two-photon sensitization dynamic treatment. The invention adopts the supermolecule self-assembly drive of the metal porphin complex to construct the functionalized metal-organic framework material ZnTPyP-MOF, and the physical and chemical properties of the original assembly molecule ZnTPyP are kept and simultaneously new optical and structural properties are endowed. The MOF is used as an inner core to grow shell titanium oxide, and then a layer of polylysine is coated, so that the high-performance two-photon diagnosis and treatment type nano biological probe is obtained. The nanoprobe has good biological safety and dispersibility, and ZnTPyP-MOF has good two-photon absorption and fluorescence emission performances, so that sensitization kinetic treatment under two-photon activation is realized; the invention can be widely used for in-situ fluorescence diagnosis and treatment of various diseases, particularly cancers, and has very important significance in clinical medicine. |
| priorityDate | 2017-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 46.