http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106967095-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J31-0285 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D513-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J31-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D513-04 |
| filingDate | 2017-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106967095-B |
| titleOfInvention | A kind of method for catalyzing the preparation of benzothiazolequinazoline derivatives |
| abstract | The invention discloses a method for catalyzing the preparation of benzothiazolequinazoline derivatives, and belongs to the technical field of ionic liquid catalysis. In this preparation reaction, the molar ratio of 2-aminobenzothiazole derivative, α-tetralone and aldehyde is 1:1:(1～1.1), and the molar dosage of the bissulfonate acidic ionic liquid catalyst is the 2-amino acid used 5～8% of the molar amount of the benzothiazole derivative, the volume of the reaction solvent water in millimoles is 5 to 7 times the molar amount of the 2-aminobenzothiazole derivative in millimoles, and the reaction temperature is 65～ 78° C., the reaction time is 24-57 min; after the reaction is completed, it is cooled to room temperature, filtered with suction, and the filter residue is washed with ethanol and dried in vacuum to obtain the benzothiazoquinazoline derivative. Compared with the existing preparation method, the present invention has the characteristics of less catalyst usage, relatively stable catalytic activity, easy biodegradation, simple and convenient operation in the whole preparation process, high degree of greenness, etc., and is easy to realize large-scale industrial production. |
| priorityDate | 2017-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 50.