http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106957324-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-10 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-10 |
filingDate | 2016-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-106957324-B |
titleOfInvention | Sequiterpene spiro lactone compounds and its preparation method and application |
abstract | The invention belongs to pharmaceutical technology fields, are related to sequiterpene spiro lactone compounds and its preparation method and application, and in particular to the preparation method of sequiterpene spiro lactone compounds and its purposes as protein-tyrosine phosphatase 1B inhibitor in abies beshanzuensis.The present invention from abies beshanzuensis ( Abies beshanzuensis ) bark in extract the Bisabolane sesquiterpene spiro lactone compounds of isolated formula (I), show that such compound can significantly inhibit PTP 1B (PTP1B) through biological activity test, the disease medicament for being further useful for preparation prevention, delaying or treat diabetes, obesity and its complication and other PTP1B mediation. (I). |
priorityDate | 2016-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 150.